Figure 3From: Evaluation of a new high-dimensional miRNA profiling platform Average bias curves. Average bias curves (i.e. the loess smoothers) from MVA plots examining reproducibility in light of various systematic factors. The left set of six are pre-normalization; the right set of six are post-normalization. (A) Within plate technical replicates for the four cell lines on all four SAMs (n = 16 curves). (B) Within plate patient technical replicates for 200 ng of extraction 1 on first three SAMs (n = 15 curves). (C) Cell line technical replicates between SAMs (n = 24 curves). (D) Patient sample technical replicates between SAMs for 200 ng of extraction 1 (n = 15 curves). (E) Patient sample between extraction technical replicate for 200 ng (n = 5 curves). Replicate 1 was chosen arbitrarily. (F) Patient samples from extraction 1 comparing 25, 100, 400, 800 ng to 200 ng for two patients (n = 10 curves). Replicate 1 for 200 ng was chosen arbitrarily.Back to article page