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Figure 6 | BMC Medical Genomics

Figure 6

From: Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells

Figure 6

The most prominently affected gene network in response to FA in TM 93 cells. Network was classified as: Cell Cycle, Cell-mediated Immune Response, Cellular Assembly and Organization. Regulation of this network in TM 93 cells is compared across treatment with DEX, FA or TA. Pathway contains jumonji, AT rich interactive domain 1B transcriptional repressor (JARID1B), which occupies a central position in this network. Red: induction; green: repression; white: unaffected; color intensity correlates with fold change; number: fold change. The diagram was obtained from Ingenuity Pathway Analysis (Ingenuity® Systems).

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