No | Network | GO Processes | Total nodes | Root nodes | p-Value |
---|---|---|---|---|---|
1 | ESR1 (nuclear) | positive regulation of retinoic acid receptor signaling pathway (16.7%; 1.463e-03), negative regulation of mitosis (16.7%; 2.194e-03), epithelial cell maturation (16.7%; 2.559e-03), regulation of retinoic acid receptor signaling pathway (16.7%; 2.925e-03), melanosome localization (16.7%; 4.019e-03) | 6 | 5 | 3.20E-18 |
2 | HNF4-alpha | negative regulation of protein import into nucleus, translocation (16.7%; 7.318e-04), negative regulation of tyrosine phosphorylation of Stat5 protein (16.7%; 1.463e-03), regulation of protein import into nucleus, translocation (16.7%; 1.829e-03), ornithine metabolic process (16.7%; 2.559e-03), positive regulation of gluconeogenesis (16.7%; 2.559e-03) | 6 | 5 | 3.20E-18 |
3 | Androgen receptor | prostate gland development (40.0%; 4.905e-06), male somatic sex determination (20.0%; 3.050e-04), somatic sex determination (20.0%; 6.099e-04), gland development (40.0%; 7.323e-04), urogenital system development (40.0%; 7.845e-04) | 5 | 4 | 1.44E-14 |
4 | HNF1-alpha | glucose homeostasis (66.7%; 5.376e-05), carbohydrate homeostasis (66.7%; 5.376e-05), epithelial cell maturation (33.3%; 1.280e-03), bile acid biosynthetic process (33.3%; 1.646e-03), paraxial mesoderm formation (33.3%; 1.829e-03) | 3 | 2 | 1.89E-07 |
5 | HNF3-beta | neuron fate specification (66.7%; 2.343e-06), positive regulation of neuron differentiation (66.7%; 6.156e-06), neuron fate commitment (66.7%; 2.409e-05), cell fate specification (66.7%; 3.555e-05), epithelial cell differentiation (66.7%; 6.683e-05) | 3 | 2 | 1.89E-07 |