Figure 3

A significant Diagnosis × Glucose deprivation × Probeset interaction effect on ERO1L expression was detected by exon array. (a) Exon array probeset expression levels are shown for the entire transcript. The probe set number is shown on the x-axis and the average expression for each diagnosis group is depicted on the y-axis. There was a significant Diagnosis × Probeset interaction effect on ERO1L expression, with a significant decrease in ERO1L expression in subjects with schizophrenia (shown in blue) compared to controls (shown in red). (b) The probeset with the most significant diagnosis effect was probeset 3564812 (p = 0.0025) and is depicted by dot plot. These findings were validated by qPCR (p = 0.0037).