Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation

Table 1 Lymphoblastoid cell lines (LCLs) from ten subjects were grown under normal conditions or under glucose deprivation.

Diagnosis	Relationship	Pair	Age	RIN (Normal Glucose)	RIN (Glucose Deprivation)	28S/18S (Normal Glucose)	28S/18S (Glucose Deprivation)
Schizophrenia	Brothers	1	43	9.8	10.0	2.0	1.7
Unaffected	Brothers	1	53	10.0	10.0	1.6	1.7
Schizophrenia	Brothers	2	48	9.5	10.0	1.6	1.9
Unaffected	Brothers	2	32	9.1	9.9	2.0	1.6
Schizophrenia	Brothers	3	45	9.6	9.6	1.6	1.5
Unaffected	Brothers	3	46	9.6	8.6	2.0	1.6
Schizophrenia	Uncle	4	33	10	10.0	1.9	1.7
Unaffected	Nephew	4	22	9.9	10.0	1.5	1.7
Schizophrenia	Cousins	5	47	9.4	10.0	1.7	1.5
Unaffected	Cousins	5	63	9.6	9.8	1.7	1.6

LCLs (N = 20) for five pairs of age- and sex- matched subjects before and after glucose deprivation were assayed by exon array. RNA quality was assessed by Agilent prior to exon array and all samples were found to have acceptable 28S/18S ratios and RNA Integrity Numbers (RIN).

ISSN: 1755-8794