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Table 4 There was a significant effect of genotype at two SNPs on IRF5 expression according to the mRNA by SNP Browser data which supported the investigation of the effects of these SNPs on probeset expression in the present study.

From: Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation

Gene

Location

Affymetrix Probeset ID

SNP Marker

Effect Size

LOD

p-value

IRF5

7q32

205468_s_at

rs4728142

-0.521

9.527

3.50E-11

IRF5

7q32

205468_s_at

rs10488630

-0.381

4.937

1.90E-06

  1. The top 25 Diagnosis × Probeset transcripts were examined in mRNA by SNP Browser software [28, 30, 29] to identify SNPs associated with candidate gene expression from LCLs. This table lists the SNP associated with each Affymetrix U133 probeset ID, with the associated effect size, logarithm of the odds (LOD) score and p-value that were obtained from mRNA by SNP Browser data.