Figure 3From: Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity Validation of expression patterns of selected genes differentially expressed in the PLN of NOD mice. A and B: Reg2 and Reg3a genes (A: Real Time PCR and B: arrays row data). C and D: Ins1 and Ins2 genes (C: Real Time PCR; D: arrays row data). Samples are PLN RNA from E-IAApos mice (A9.6 & A15.4) and from E-IAA neg mice (A12.2 & A8.1). E, F &G. Staining of histological sections with anti-Insulin antibodies, from pancreas (E), PLN (F) and Inguinal lymph nodes (G) from NOD mouse at 5 weeks.Back to article page