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Table 3 LGALS4, ACS5 and CLU expression in 26 sinonasal adenocarcinomas (IHC analysis).

From: Gene expression profiling in sinonasal adenocarcinoma

Patient

Tumor subtypes (Barnes'classification [25])

CLUa

ACS5

LGALS4

1

ITAC mixed (papillary and mucinous)

-

-

+++

2

ITAC mucinous

-

-

+++

3

ITAC mucinous

-

-

+++

4

ITAC colonic

-

+

+++

5

ITAC mixed (solid and colonic)

-

++

-/++

6

ITAC mucinous

-

+

+++

7*

ITAC mucinous

-

-

+++

8

ITAC mucinous

-

-

+++

9

ITAC mixed (papillary and mucinous)

-

+++

+++

10**

non ITAC high-grade

-

-

-

11

non ITAC high-grade

+++

++

-

12

ITAC papillary

-

+++

+++

13

ITAC mucinous

-

-

+++

14

ITAC papillary

-

-

+++

15

ITAC mucinous

-

-

+++

16

ITAC mixed (papillary and mucinous)

-

++

+++

17

ITAC papillary

-

++

+++

18

ITAC mixed (papillary, colonic and mucinous)

-

+

+

19*

ITAC mucinous

-

+

+++

20

ITAC mixed (colonic and mucinous)

-

+

+++

21

ITAC mixed (papillary and mucinous)

-

-

+++

22

ITAC papillary

-

-

+++

23

ITAC mixed (papillary and colonic)

-

-

+++

24

ITAC colonic

-

+++

++

25

ITAC papillary

-

+

+++

26

ITAC mucinous

-

-

+++

  1. * Patients exposed to leather dust
  2. ** No occupational exposure
  3. a- Intensity of immunostaining in tumoral cells:
  4. +++: positivity of 75 to 100% of cells with an strong staining.
  5. ++: positivity of 25 to 75% of cells with heterogenous weak to strong staining.
  6. +: focal and weak positivity of 1 to 25% of cells.
  7. -: no staining.