Figure 1

Volcano plots of the gene list as yielded by ANOVA. Each panel represents filtered and normalized data from each experimental time point (3, 6, 12, 24 and 48 h). The horizontal axes depict the fold change ratio between treatment with mastic oil and vehicle for each time point in log₂ scale while the vertical axes represent statistical significance by depicting the -log₁₀(p-value). Larger values in the vertical axes represent larger statistical significance. Differentially expressed genes (fold change>|0.2| in log₂ scale, p-value < 0.05, FDR < 0.05) are shown in each panel where down-regulated genes are depicted by green dots and up-regulated genes by red dots. Non differentiated genes are shown as blue dots. Dashed lines indicate fold change thresholds and solid lines indicate the statistical significance (p-value) threshold. The p-value threshold of 0.05 corresponds to the value 1.3 in the vertical axes using the aforementioned transformation.