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Table 3 Selected Major Genes and Disease Phenotypes

From: Systematic analysis, comparison, and integration of disease based human genetic association data and mouse genetic phenotypic information

Gene   Gene  
APOE ALZHEIMER DISEASE (70) VDR PROSTATIC NEOPLASMS (10)
  CORONARY DISEASE (8)   OSTEOPOROSIS, POSTMENOPAUSAL (8)
  CARDIOVASCULAR DISEASES (7)   BREAST NEOPLASMS (7)
  MYOCARDIAL INFARCTION (6)   DIABETES MELLITUS, TYPE 1 (6)
  DIABETES MELLITUS, TYPE 2 (6)   OSTEOPOROSIS (6)
ACE HYPERTENSION (47) MTHFR NEURAL TUBE DEFECTS (6)
  DIABETES MELLITUS, TYPE 2 (25)   COLORECTAL NEOPLASMS (5)
  MYOCARDIAL INFARCTION (17)   DIABETES MELLITUS, TYPE 2 (5)
  CORONARY DISEASE (16)   ESOPHAGEAL NEOPLASMS (5)
  DIABETIC NEPHROPATHIES (15)   ADENOCARCINOMA (4)
HLA-DQB1 DIABETES MELLITUS, TYPE 1 (30) CYP17A1 BREAST NEOPLASMS (10)
  PAPILLOMAVIRUS INFECTIONS (7)   PROSTATIC NEOPLASMS (9)
  CELIAC DISEASE (6)   PROSTATIC HYPERPLASIA (4)
  AUTOIMMUNE DISEASES (5)   OSTEOPOROSIS, POSTMENOPAUSAL (3)
  TUBERCULOSIS, PULMONARY (5)   ENDOMETRIAL NEOPLASMS (2)
DRD2 ALCOHOLISM (17) ADRB2 ASTHMA (12)
  SCHIZOPHRENIA (14)   OBESITY (10)
  PERSONALITY DISORDER (2)   HYPERTENSION (8)
  DEPRESSIVE DISORDER (2)   DIABETES MELLITUS, TYPE 2 (4)
  DYSKINESIA, DRUG INDUCED (2)   BRONCHIAL HYPERREACTIVITY (4)
PPARG DIABETES MELLITUS, TYPE 2 (18) NOS3 HYPERTENSION (20)
  OBESITY (11)   MYOCARDIAL INFARCTION (18)
  DIABETES MELLITUS (6)   CORONARY ARTERY DISEASE (15)
  INSULIN RESISTANCE (4)   CORONARY DISEASE (12)
  GLUCOSE INTOLERANCE (2)   DIABETES MELLITUS, TYPE 2 (10)