Advertisement
Table 3 Selected Major Genes and Disease Phenotypes
| Gene | Gene | ||
|---|---|---|---|
| APOE | ALZHEIMER DISEASE (70) | VDR | PROSTATIC NEOPLASMS (10) |
| CORONARY DISEASE (8) | OSTEOPOROSIS, POSTMENOPAUSAL (8) | ||
| CARDIOVASCULAR DISEASES (7) | BREAST NEOPLASMS (7) | ||
| MYOCARDIAL INFARCTION (6) | DIABETES MELLITUS, TYPE 1 (6) | ||
| DIABETES MELLITUS, TYPE 2 (6) | OSTEOPOROSIS (6) | ||
| ACE | HYPERTENSION (47) | MTHFR | NEURAL TUBE DEFECTS (6) |
| DIABETES MELLITUS, TYPE 2 (25) | COLORECTAL NEOPLASMS (5) | ||
| MYOCARDIAL INFARCTION (17) | DIABETES MELLITUS, TYPE 2 (5) | ||
| CORONARY DISEASE (16) | ESOPHAGEAL NEOPLASMS (5) | ||
| DIABETIC NEPHROPATHIES (15) | ADENOCARCINOMA (4) | ||
| HLA-DQB1 | DIABETES MELLITUS, TYPE 1 (30) | CYP17A1 | BREAST NEOPLASMS (10) |
| PAPILLOMAVIRUS INFECTIONS (7) | PROSTATIC NEOPLASMS (9) | ||
| CELIAC DISEASE (6) | PROSTATIC HYPERPLASIA (4) | ||
| AUTOIMMUNE DISEASES (5) | OSTEOPOROSIS, POSTMENOPAUSAL (3) | ||
| TUBERCULOSIS, PULMONARY (5) | ENDOMETRIAL NEOPLASMS (2) | ||
| DRD2 | ALCOHOLISM (17) | ADRB2 | ASTHMA (12) |
| SCHIZOPHRENIA (14) | OBESITY (10) | ||
| PERSONALITY DISORDER (2) | HYPERTENSION (8) | ||
| DEPRESSIVE DISORDER (2) | DIABETES MELLITUS, TYPE 2 (4) | ||
| DYSKINESIA, DRUG INDUCED (2) | BRONCHIAL HYPERREACTIVITY (4) | ||
| PPARG | DIABETES MELLITUS, TYPE 2 (18) | NOS3 | HYPERTENSION (20) |
| OBESITY (11) | MYOCARDIAL INFARCTION (18) | ||
| DIABETES MELLITUS (6) | CORONARY ARTERY DISEASE (15) | ||
| INSULIN RESISTANCE (4) | CORONARY DISEASE (12) | ||
| GLUCOSE INTOLERANCE (2) | DIABETES MELLITUS, TYPE 2 (10) |
