|
A4galt
|
A4GALT
|
abnormal induced morb./mort.
|
abnormal resp./metab. to xenobiotics
|
life span-post-weaning/aging
|
homeostasis/metab. phenotype
| |
|
Abca2
|
ABCA2
|
tremors
|
decreased body weight
|
behavior/neurological phenotype
|
hyperactivity
|
increased startle reflex
|
|
Abcc2
|
ABCC2
|
abnormal blood chemistry
|
abnormal liver physiology
|
abnormal urine chemistry
|
abnormal kidney physiology
|
Abn. resp./metabolism to xenobiotics
|
|
Abi2
|
ABI2
|
abn. corpus callosum morph.
|
abnormal cerebral cortex morph.
|
abnormal hippocampus morph.
|
abnormal dentate gyrus morph.
|
microphthalmia
|
|
Acaca
|
ACACA
|
abnormal liver physiology
|
abnormal lipid level
|
incr. circulating free fatty acid level
|
hyperglycemia
|
embryonic growth arrest
|
|
Acads
|
ACADS
|
hypoglycemia
|
behavior/neurological phenotype
|
abnormal drinking behavior
|
abnormal food preference
|
abnormal urine chemistry
|
|
Accn1
|
ACCN1
|
retinal degeneration
|
vision/eye phenotype
|
abnormal eye electrophysiology
| | |
|
Adad1
|
ADAD1
|
impaired fertilization
|
male infertility
|
asthenozoospermia
|
oligozoospermia
|
reproductive system phenotype
|
|
Adam23
|
ADAM23
|
tremors
|
behavior/neurological phenotype
|
ataxia
|
postnatal lethality
|
lethality-postnatal
|
|
Adarb1
|
ADARB1
|
behavior/neurological phenot.
|
seizures
|
postnatal lethality
|
behavior/neurological phenotype
|
normal phenotype
|
|
Adipoq
|
ADIPOQ
|
vasculature congestion
|
increased body weight
|
decreased body weight
|
abnormal CNS syn. transmission
|
abnormal coat appearance
|
|
Adora1
|
ADORA1
|
behavior/neurological phenot.
|
increased anxiety-related response
|
abnormal body temperature regulation
|
abnormal angiogenesis
|
abnormal nervous system electrophys.
|
|
Ager
|
AGER
|
increased bone density
|
abnormal cancellous bone morph.
|
abnormal blood chemistry
|
reproductive system phenotype
|
abnormal cell proliferation
|
|
Akap1
|
AKAP1
|
reduced female fertility
|
decreased litter size
|
abnormal female meiosis
|
increased cholesterol level
| |
|
Apoc1
|
APOC1
|
abnormal circ. cholesterol level
|
abnormal lipid level
|
increased circulating triglyceride level
|
abnormal immune sys. Morph.
|
abnormal bile composition
|
|
B2m
|
B2M
|
decreased hematocrit
|
abnormal interleukin-10 physiology
|
rectal prolapse
|
abnormal dorsal root gang. morph.
|
enlarged spleen
|
|
Bax
|
BAX
|
enlarged spleen
|
increased thymocyte number
|
abnormal motor neuron morph.
|
short snout
|
abnormal sympathetic neuron morph.
|
|
Bcl2
|
BCL2
|
small ears
|
absent melanin granules in hair follicle
|
abnormal snout morph.
|
herniated abdominal wall
|
abnormal small intestine morph.
|
|
Bmp1
|
BMP1
|
abnormal heart morph.
|
abnormal aorta morph.
|
abnormal ventricular septum morph.
|
abnormal awl hair
|
prenatal lethality
|
|
Brca1
|
BRCA1
|
abnormal cell death
|
increased cell proliferation
|
decreased cell proliferation
|
decreased anxiety-related resp.
|
kinked tail
|
|
Capn10
|
CAPN10
|
abnormal pancreas physiology
|
endocrine/exocrine gland phenotype
|
digestive/alimentary phenotype
|
decreased inflammatory response
| |
|
Casp1
|
CASP1
|
abnormal apoptosis
|
abnormal induced morbidity/mortality
|
abnormal inflammatory response
|
decr. suscep. to endotoxin shock
|
tumorigenesis
|
|
Ccr4
|
CCR4
|
immune system phenotype
|
decreased tumor necrosis factor secr.
|
decreased interleukin-1 beta secretion
|
abnormal induced morbid./mort.
| |
|
Dusp1
|
DUSP1
|
thick alveolar septum
|
abnormal circ. alanine transaminase
|
hypotension
|
increased thymocyte number
|
lung inflammation
|
|
E2f1
|
E2F1
|
abnormal cell death
|
decreased salivation
|
enlarged thymus
|
pale liver
|
exencephaly
|
|
Epo
|
EPO
|
abnormal erythropoiesis
|
abnormal pericardium morph.
|
small liver
|
postnatal growth retardation
|
abnormal hepatocyte morph.
|
|
Ercc4
|
ERCC4
|
abnormal cell content/morph.
|
abnormal liver morph.
|
decreased body weight
|
absent blood islands
|
liver/biliary system phenotype
|
|
F5
|
F5
|
behavior/neurological phenot.
|
abnormal somite development
|
abnormal yolk sac morph.
|
increased suscep. to bact. Infect.
|
hemorrhage
|
|
Fcgr1
|
FCGR1A
|
impaired macrophage phagocyt.
|
abnormal inflammatory response
|
decreased inflammatory response
|
abnormal yolk sac morph.
|
abnormal cell-mediated immunity
|
|
Foxo1
|
FOXO1
|
absent organized vascular net.
|
abnormal looping morphogenesis
|
abnormal vasculature
|
exencephaly
|
absent vitelline blood vessels
|
|
Gadd45a
|
GADD45A
|
decreased leukocyte cell num.
|
increased cell proliferation
|
increased thymocyte number
|
postnatal lethality
|
skin irradiation sensitivity
|
|
Gap43
|
GAP43
|
decreased body weight
|
abnormal optic nerve innervation
|
absent optic tract
|
abnormal erythropoiesis
|
nervous system phenotype
|
|
Gata1
|
GATA1
|
decreased hematocrit
|
abnormal thrombopoiesis
|
extramedullary hematopoiesis
|
overexpanded resp. alveoli
|
liver hypoplasia
|
|
Grin1
|
GRIN1
|
abn. trigeminal nerve morph.
|
atelectasis
|
lung hemorrhage
|
abnormal tympanic ring morph.
|
decreased body weight
|
|
Hoxa1
|
HOXA1
|
small ears
|
abnormal inner ear morph.
|
abnormal malleus morph.
|
increased susceptibility to injury
|
abnormal cochlea morph.
|
|
Hspa1a
|
HSPA1A
|
decreased body weight
|
increased cell. Sens. to gamma-irrad.
|
chromosome breakage
|
increased body weight
|
homeostasis/metabolism phenotype
|
|
Icam1
|
ICAM1
|
increased leukocyte cell number
|
increased neutrophil cell number
|
increased monocyte cell number
|
abnormal spatial learning
|
abnormal retina morph.
|
|
Igbp1
|
IGBP1
|
decreased thymocyte number
|
behavior/neurological phenotype
|
abnormal cued conditioning behavior
|
intestinal ulcer
|
abnormal thymus lobule morph.
|
