Table 1 Sequence variants identified in ASMT, MTNR1A, MTNR1B in patients with ASD.
From: Mutation screening of melatonin-related genes in patients with autism spectrum disorders
Gene | Location/ nucleotide change | Amino acid change | Cases (n = 109) | Controls (n = 188) |
|---|---|---|---|---|
ASMT | c.-376G>A | - | 1 | 1 |
ASMT | c.-38C>T | - | 1 | 0 |
ASMT | IVS5+2T>C | - | 1 | 0 |
MTNR1A | c.-158C>T | - | 1 | 0 |
MTNR1B | c.370G>A | V124I* | 1 | 0 |
MTNR1B | c.-39GC>AA | - | 1 | 0 |