Skip to main content

Table 1 Information on biological processes based on Gene ontology.

From: Genomics and proteomics approaches to the study of cancer-stroma interactions

Biological Process Down-regulated genes
Cell communication  
   signal transduction FAS, SQSTM1, YWHAZ
Transcription ARID4A, CALR, MYC, PARP1, RNF10, SQSTM1
Translation AARS, RPLP0, RPS17, RPS23
Apoptosis CALR
   induction FAS
   anti-apoptosis TPT1, YWHAZ
Cell migration TMSB4X
Cell cycle DYNC1H1, MYC, PSMC6
Cell proliferation  
   negative regulation GPNMB, LDOC1
   positive regulation MYC
Developmental process  
   epidermis development UGCG
Response to stimulus  
   defense response  
inflammatory response LTA4H
   response to stress EIF2AK1, SQSTM1
response to oxidative stress  
   response to external stimulus EIF2AK1
Transport CALR, NDUFA4, SQSTM1
Metabolic process COX7C, OLA1,
   protein metabolic process PARP1, SQSTM1, USP9X
protein modification process GRPEL2, HSP90AB1, PPP2R2A, PRPF4B, USP48
   lipid metabolic process LTA4H, UGCG
   DNA repair PARP1
   RNA processing PRPF4B, SF3B1
Cellular homeostasis CALR, MYC, RPS17
No classification GNB2L1, RCN1
  Up-regulated genes
Transcription ENO1
Translation EIF1, TARS
Apoptosis RTN3
   induction DAP3
Cell proliferation PRDX1
   negative regulation ENO1
Developmental process  
   organ development PRDX1
Response to stimulus  
   response to stress EIF1, RTN3
Metabolic process PRDX1
   protein metabolic process  
protein modification process P4HB
   nucleic acid metabolic process  
RNA processing USP39
  1. Top down- and up-regulated genes selected by RaSH in Hep-2 samples treated with FCM.