Table 1 Information on biological processes based on Gene ontology.
From: Genomics and proteomics approaches to the study of cancer-stroma interactions
| Biological Process | Down-regulated genes |
|---|---|
| Cell communication | |
| signal transduction | FAS, SQSTM1, YWHAZ |
| Transcription | ARID4A, CALR, MYC, PARP1, RNF10, SQSTM1 |
| Translation | AARS, RPLP0, RPS17, RPS23 |
| Apoptosis | CALR |
| induction | FAS |
| anti-apoptosis | TPT1, YWHAZ |
| Cell migration | TMSB4X |
| Cell cycle | DYNC1H1, MYC, PSMC6 |
| Cell proliferation | |
| negative regulation | GPNMB, LDOC1 |
| positive regulation | MYC |
| Developmental process | |
| epidermis development | UGCG |
| Response to stimulus | |
| defense response | |
| inflammatory response | LTA4H |
| response to stress | EIF2AK1, SQSTM1 |
| response to oxidative stress | |
| response to external stimulus | EIF2AK1 |
| Transport | CALR, NDUFA4, SQSTM1 |
| Metabolic process | COX7C, OLA1, |
| protein metabolic process | PARP1, SQSTM1, USP9X |
| protein modification process | GRPEL2, HSP90AB1, PPP2R2A, PRPF4B, USP48 |
| lipid metabolic process | LTA4H, UGCG |
| DNA repair | PARP1 |
| RNA processing | PRPF4B, SF3B1 |
| Cellular homeostasis | CALR, MYC, RPS17 |
| No classification | GNB2L1, RCN1 |
| Up-regulated genes | |
| Transcription | ENO1 |
| Translation | EIF1, TARS |
| Apoptosis | RTN3 |
| induction | DAP3 |
| Cell proliferation | PRDX1 |
| negative regulation | ENO1 |
| Developmental process | |
| organ development | PRDX1 |
| Response to stimulus | |
| response to stress | EIF1, RTN3 |
| Metabolic process | PRDX1 |
| protein metabolic process | |
| protein modification process | P4HB |
| nucleic acid metabolic process | |
| RNA processing | USP39 |