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Table 2 Information on biological processes based on Gene Ontology.

From: Genomics and proteomics approaches to the study of cancer-stroma interactions

Biological Process

Down-regulated genes

Cell communication

 

   signal transduction

S100A6, FN1

Transcription

FOSL1

Translation

RPL37A, RPL7, RPL19, RPL27A, RPLP0

Apoptosis

CTSB

   anti-apoptosis

TPT1

Cell adhesion

FN1

Cell proliferation

 

   positive regulation

S100A6, FOSL1

Developmental process

 

   organ development

 

epidermis development

COL1A1

Response to stimulus

 

   defense response

FOSL1

   response to stress

FN1

Transport

ERGIC3, STX4

Metabolic process

 

   protein metabolic process

CTSB

   RNA processing

PRPF3

No classification

CIZ1, POLE4

  1. Top down-regulated genes selected by RaSH in CAF samples treated with HCM.