Table 4 Univariate and multivariate analysis of clinical variables affecting 5-year survival of lung cancer patients, including our classifier, with hazard ratios (HR).
From: MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients
Clinical variable | Comparison | p-value (univariate) | p-value (multivariate) | HR |
|---|---|---|---|---|
T stage | T1-2 vs. T3-4 | 1 × 10 -7 | 1.77 × 10 -5 | 2.6 |
N stage | Nodes uninvolved (N0) vs. Nodes involved (N1-2) | 2.84 × 10 -12 | 2.29 × 10 -11 | 2.8 |
Tumor grade | Low grade (1) vs. intermediate or high grade (2-3) | 0.12 | 0.37 | 1.3 |
Our classifier (MAPS) | MAPS- vs. MAPS+ (Expressor) | 4.66 × 10 -6 | 0.0001 | 1.8 |