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Table 4 Prediction of environmental chemicals associated with breast cancer samples (GSE6883).

From: Predicting environmental chemical factors associated with disease-related gene expression data

Chemical Predicted Hypergeometric P-value Rank (percentile) q-value Relevant genes in set (number of references) Citations
Progesterone 2 × 10-4 6 (99) 0.01 IL6(3), STC1(3), CEBPD(2) [64, 65]
Genistein 6 × 10-4 10 (99) 0.03 CEBPD(1), APLP2(1), MLF1(1) [6668]
Estradiol 7 × 10-4 11 (99) 0.03 LPL(4), IL6(3), CEBPD(2) [6973]
Indomethacin 3 × 10-3 17 (99) 0.05 CCDC50(1), BIRC3(1), DNAJB(1) [74]
Diethylstilbestrol 3 × 10-3 18 (99) 0.05 IL6(1), MARCKS(1), MXD1(1), MMP7(1) [75, 76]
Cyclophosphamide 4 × 10-4 19 (99) 0.06 IL6(3), MARCKS(1), PSMA5(1) [7779]
Bisphenol A 6 × 10-3 21 (99) 0.08 CEBPD(1), MLF1(1), DTL(1) [80]
  1. Shown in the table are a subset of the highly ranked chemicals (p < 0.01) that were predicted to have association with breast cancer gene expression (non-tumorigenic) and had evidence of association with the MeSH term "Breast Neoplasms". Columns have similar definitions as Table 2.