Duration | Top ranked proteins |
---|
0~1HR
| IRAK1 | NIK | IKKα | TRAF6 | IKKβ |
1~2HR
| TRAF6 | IRAK1 | NIK | A20 | TRAF2 |
2~3HR
| IRAK1 | TRAF6 | NIK | A20 | TRAF2 |
3~4HR
| IRAK1 | NIK | TRAF6 | A20 | IKKγ |
4~6HR
| IRAK1 | TRAF6 | NIK | TRAF2 | A20 |
6~8HR
| IRAK1 | NIK | TRAF6 | IKKα | A20 |
- In contract with Table 2, proteins with maximal CTRVs are listed here. Among these highly ranked proteins, NIK and A20 are considered as two core elements in the signaling network by the analysis of CTRV, but their importance is not exhibited in Table 2. This reveals that our proposed method generates a new insight into the evaluation of cross-talk candidates.