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Table 1 Genes specific to the erythroid and megakaryoblastic leukaemias

From: Gene profiling of the erythro- and megakaryoblastic leukaemias induced by the Graffi murine retrovirus

probeset gene SAM results * Leukaemic samples**
   d-score FDR T1 T2 T3 B1 B2 B3 M E1 E2 E3 Mk1 MK2 Mk3
Fibrinogen receptor and related genes
1417758_at Itga2b 10.58 <0.001 -2.7 -1.6 -2.6 -2.9 -2.6 -2.7 -1.6 3.8 0.8 1.1 3.6 3.6 3.8
1421511_at Itgb3 - >0.01 -1.0 -0.7 -0.7 -0.8 -0.7 -0.9 -0.6 1.6 -0.7 -0.7 -0.6 2.9 3.1
1416066_at Cd9 5.5 0.002 1.1 -2.5 2.5 -3.5 -3.6 -3.6 0.6 1.9 -1.8 -2.1 3.0 4.4 3.5
1456085_x_at Cd151 7.56 <0.001 -1.2 -1.1 -0.7 -0.7 -0.9 -0.6 -0.3 1.4 -0.2 -0.3 1.8 0.8 2.1
1420558_at Selp 12.03 <0.001 -1.0 -1.2 -1.9 -1.6 -1.5 -1.7 -1.1 -0.9 -1.7 -1.6 4.3 5.7 4.1
1457782_at Tln1 7.19 <0.001 -0.7 -0.4 -1.4 -0.3 -0.8 -1.0 0.9 2.3 -1.5 -0.5 0.8 1.4 1.3
1424595_at F11r 5.58 0.002 -0.9 -0.8 -0.9 -0.8 -0.6 -1.0 -0.6 0.2 -0.6 -0.6 2.0 3.1 1.5
1451097_at Vasp 5.24 <0.001 -0.8 -1.3 0.1 0.3 -0.3 0.3 0.7 0.0 -0.6 -1.0 0.8 1.2 0.7
1418261_at Syk 16.04 <0.001 -2.4 -2.8 -2.8 2.9 2.5 2.8 1.4 -1.5 -2.0 -3.1 1.5 1.6 1.8
1455349_at Rap1b 4.63 <0.001 -0.7 -0.8 -1.1 -0.6 -1.2 -1.0 -0.2 2.1 -0.3 0.9 0.7 0.9 1.4
Heme biosynthesis
1451675_a_at Alas2 8.85 <0.001 -3.4 0.3 -0.9 -2.5 -3.8 -3.2 -1.3 4.9 4.9 4.8 -2.8 -0.5 3.5
1424877_a_at Alad 8.91 <0.001 -1.2 -0.4 0.0 -1.3 -1.6 -0.7 -1.6 2.2 2.2 2.0 0.4 -0.9 1.2
1426475_at Hmbs 13.44 <0.001 -1.2 -1.0 -0.4 -1.5 -1.1 -1.1 -1.1 2.6 3.4 2.7 -0.8 -0.9 0.5
1423482_at Uros - - -0.6 -0.3 -0.2 -0.3 0.1 0.2 -0.9 0.7 1.5 0.2 0.0 -0.5 0.0
1417206_at Urod 10.87 <0.001 0.0 -0.4 -0.3 -1.2 -0.9 -1.0 -0.3 1.8 1.6 1.4 -0.6 -0.5 0.3
1422493_at Cpox 22.18 <0.001 -1.6 -1.2 -0.2 -0.5 -0.8 -1.0 -1.5 2.7 3.1 3.2 -1.0 -0.7 -0.4
1416618_at Ppox 4.58 0.004 -0.5 -0.1 -0.3 0.1 -0.2 -0.4 0.0 0.7 1.4 0.6 -0.6 -0.4 -0.4
1418699_s_at Fech 8.61 <0.001 -0.7 -1.0 -0.3 -1.9 -1.9 -2.0 -0.4 2.5 3.1 2.2 -0.7 0.0 1.1
Erythroid and megakaryoblastic transcription factors
EMk                 
1450333_a_at Gata2 7.4 0.01 -1.9 -1.6 -1.9 -1.7 -1.8 -1.9 -1.1 -0.6 2.2 0.6 3.4 3.4 2.8
1423603_at Zfpm1(Fog1) 5.4 0.02 -1.2 -1.7 -1.4 0.1 -0.6 -0.2 -3.9 2.0 2.0 2.0 1.3 0.8 0.9
1449389_at Scl/Tal1 20.8 <0.01 -3.3 -2.5 -3.1 -3.2 -2.5 -2.5 -2.5 4.1 3.8 3.5 2.6 2.9 2.9
1454086_a_at Lmo2 4.5 0.03 -5.1 -3.8 -4.6 0.7 -1.3 -0.9 0.7 2.8 3.0 2.9 1.3 2.5 1.8
1452001_at Nfe2 8.3 0.01 -4.2 -3.0 -3.4 -3.8 -3.0 -3.2 1.3 3.7 3.5 3.3 2.5 3.7 2.8
EMk3                 
1449232_at Gata1 4.6 0.03 -1.9 -1.9 -2.1 -2.1 -2.3 -2.7 -1.9 4.5 4.1 4.5 0.6 -1.4 2.5
MkE1                 
1441584_at Fli1 5.3 0.1 -0.2 -0.4 -0.5 0.7 0.6 0.5 0.7 2.6 -4.8 -4.9 1.8 2.4 1.6
Erythroid transcription factors
EMk3                 
1418600_at Klf1 6.8 0.04 -2.9 -2.3 -2.4 -2.7 -2.7 -2.8 -1.8 4.8 5.4 5.3 1.7 -1.7 2.1
1419311_at Trim10 8.9 0.02 -2.0 -1.4 -2.1 -2.1 -2.1 -2.0 -1.5 5.0 4.1 3.8 -1.0 -0.8 2.1
Megakaryoblastic transcription factors
MkE1                 
1421461_at Mpl 16.1 <0.001 0.07 -1.9 -1.6 -2.1 -2.0 -2.1 -2.0 -1.3 1.3 -1.0 -1.7 4.9 4.4
MkE1                 
1440878_at Runx1 4.5 0.11 0.6 -1.8 -1.0 0.2 0.2 0.5 -0.5 0.9 -0.8 -0.1 0.7 0.8 0.3
  1. * SAM p-value less than 0,001 for every sample
  2. ** amplitude of deviation from the mean calculated from the RMA values