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Table 4 Graffi-virus integration sites in the megakaryoblastic leukaemias

From: Gene profiling of the erythro- and megakaryoblastic leukaemias induced by the Graffi murine retrovirus

Sample Chromosome Genome Upstream genes* Integra-tion within a gene Downstream genes*
    gene 1 kb gene 2 kb   gene 1 kb gene 2 kb
Mk1 1D 93018002 Gm817 17 Lrrfip1 60 Ramp1** Ube2f 95 Scly 130
  1G2 153451217 Rnf2 188 1190005F20Rik 230 Niban Edem3 92 Q8K3Do 199
  4B1 41816941 2310028H24Rik 133 1700066J25Rik 138 Dnaic1 Cntfr 29 Dcnt3 86
  5E 1 75741720 Pdgfra 216 Gsh2 382 - Kit** 114 Kdr 472
  6F3 128801887 Klrb1b 10 Clec2h 159 - Clec21 50 Klrb1f 208
  6G1 135264443 Gsg1 61 Hebp1) 130 - Pbp2 10 Dynlt1 50
  11B4 70471623 Pfn1** 0.8 Rnf167 4 - Eno3 1.7 Spag7 8.2
  11B5 80139013 Rhot1 55 Rnf135 123 Rhbd13 Zfp207 60 Psmd11 105
  15D3 62283939 Pvt1 211 Myc** 463   -   -  
  15F2 95582212 Dbx2 100 Nell2 225 - -   Tmem16f 36
  16B3 33700976 Heg1 13 Slc12a8 118 - Muc13 12 Itgb5 ** 48
Mk2            
  1 E4 132543823 Pfkb2 0.4 C4bp 54 - Yod1 0.8 AA986890 1
  6A3 25759728 Pot 1a 14 Grp37 120 - -   -  
  8 E1 123703449 Irf8 81 Cox4i1 149 - Foxf1a** 269 Mthfsd 280
  12C1 52786246 Hectd1 120 EG544864 35 - Heatr5a 11 6530401NO4Rik 124
  13D2.3 116255725 Pelo 46 Itga1 33 - -   -  
Mk3            
  1C5   Glrp1 146 Spp2 230 - Arl14c 161 Sh3bp4 413
  1F 139621937 -     - Ptprc 257 Atp6v1g3 466
  2H3 165618991 Prkcbp1** 43 Eya2 156 - Ncoa3 65 Sulf2 146
  5B1 43941 Rheb 23 Cryng 83 - Prkag2** 20 1500035N22Rik 144
  6D2 88086902 Rpn1 16 EG434064 115 - Gata2** 72 Dnajb8 100
  7B4 45356428 Bax 21 Flt1 28 Dhdh Nucb1 4 Tulp2 25
  7F5 144856850 Ccnd1** 107 Oraov1 167 - Tpcn2) 167 Mrgprf 253
  13A1 3830652 Calm13 27    - Calm4 6 Calm5 22
  14C3 53491694 Prmt5 20 Rem2 57 - D14Ertd500e 4 Jub 31
  19A 4301566 Ankrd13d 18 Ssh3 32 Adrbk1** Fbxl13 15 FBXL13 15
  1. * the 2 most proximal genes located at a maximum distance of 500kb upstream (5') or downstream (3') of the integration site
  2. ** genes present in the RTCGD database