Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Heritability Estimates of factors in African American and European American pedigrees.

From: A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

  White African American
  Factor Estimate S.E. Factor Estimate S.E.
Post Aspirin Factors 1W: Collagen/TXM 0.50 0.09 1B: Collagen 0.36 0.14
  2W: Epinephrine 0.61 0.09 2B: High Dose Collagen 0.84 0.13
  3W: High Dose Collagen/TXM 0.47 0.10 3B: Epinephrine 0.46 0.15
  4W: ADP PRP 0.34 0.09 4B: ADP 0.29 0.14
  5W: ADP 0.54 0.09 5B: ADP PRP 0  
  6W: Low Dose Collagen 0.40 0.09 6B: Very Low Dose Collagen 0.32 0.15
  7W: Very Low Dose Collagen 0.31 0.09 7B: ADP/Epinephrine 0.33 0.17
  8W: ADP/Epinephrine 0.05 0.09* 8B: TXM 0.51 0.15
Post-adjusted-for-pre Aspirin Factors 1W: High Dose Collagen 0.67 0.11 1B: High Dose Collagen 0.51 0.17
  2W: Epinephrine 0.41 0.10 2B: Epinephrine 0.31 0.13
  3W: Collagen/TXM 0.40 0.10 3B: Collagen 0.43 0.20
  4W: Low Dose Collagen 0.18 0.11* 4B: Low Dose Collagen 0.08 0.12*
  5W: ADP 0.27 0.10 5B: ADP 0.15 0.13*
  6W: Low Dose Collagen 0.18 0.10* 6B: Low Dose Collagen 0.34 0.17
  7W: High Dose ADP 0.21 0.11* 7B: Epinephrine/ADP/Collagen 0.31 0.15
  8W: Epinephrine/Collagen 0.26 0.10 8B: High Dose ADP 0  
Pre Aspirin Factors 1W: Collagen 0.19 0.12* 1B: Low Dose Collagen 0.58 0.17
  2W: AA/ADP 0.61 0.10 2B: Collagen 0.19 0.22*
  3W: Low Dose Collagen 0.70 0.10 3B: Epinephrine 0.55 0.19
  4W: Collagen Lag 0.37 0.11 4B: Collagen Lag 0.1 0.13*
  5W: Epinephrine 0.51 0.10 5B: ADP 0.03 0.23*
  6W: ADP/Epinephrine 0.30 0.10 6B: Collagen Lag 0.22 0.15*
  7W: ADP/Epinephrine Lag 0.07 0.10* 7B: PFA 0.12 0.18*
  8W: PFA 0.20 0.11* 8B: AA/ADP/Collagen Lag 0.58 0.17
  1. * = not statistically significant at α = 0.05