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Table 3 Summary of multipoint linkage signals in European American pedigrees.

From: A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

Significance Criteria Chr Map Position Marker Factor
P < 0.00002 - - -  
P < 0.00074 3 89.04039 D3S1600 2W(POST):Epinephrine
  4 62.104 D4S405 3W(POST):High Dose Collagen/TXM
  4 67.63 D4S396 3W(POST):High Dose Collagen/TXM
  4 71.03 D4S428 3W(POST):High Dose Collagen/TXM
  5 203.456 D5S469 5W(PP):ADP
  6 174.4557 D6S1581 3W(PP):Collagen/TXM
  11 126.83 D11S4089 2W(POST):Epinephrine
  15 43.142 D15S146 7W(PP):High Dose ADP
  15 52.712 D15S1016 7W(PP):High Dose ADP
  1. POST = Post-ASA Factor, PRE = Pre-ASA Factor, PP = Post-adjusted-for-pre-ASA Factor, Chr = chromosome
  2. Significance criteria as defined by Lander and Kruglyak (1995): suggestive linkage (p-value < 7 × 10-4) and significant linkage (p-value < 2 × 10-5).