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Table 4 Summary of multipoint linkage signals in African American pedigrees.

From: A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

Significance Criteria Chr Map position Marker Factor
P < 0.00002 5 71.143 D5S628 4B(POST):ADP
  5 80.82 D5S2072 4B(POST):ADP
P < 0.00074 1 160.45 D1S484 2B(PRE):Collagen
  1 216.774 D1S245 4B(POST):ADP
  1 217.215 D1S205 4B(POST):ADP
  2 78.417 D2S2156 5B(POST):ADP PRP
  5 83.18814 D5S1967 4B(POST):ADP
  8 69.341 D8S1737 4B(POST):ADP
  11 154.04129 D11S969 4B(POST):ADP
  17 102.596 D17S940 5B(PP): ADP
  18 21.744 D18S967 7B(POST): ADP/Epinephrine
  19 99.84163 D19S572 4B(PRE):Collagen Lag
  1. POST = Post-ASA Factor, PRE = Pre-ASA Factor, PP = Post-adjusted-for-pre-ASA Factor, Chr = chromosome
  2. Significance criteria as defined by Lander and Kruglyak (1995): suggestive linkage (p-value < 7 × 10-4) and significant linkage (p-value < 2 × 10-5).