RAS signature distribution across non-small cell lung (A) and breast (B) cancer subsets. The Y-axis shows RAS signature score relative to the mean of all non-small cell lung (A) or breast (B) tumors in the dataset. For (B), GGI = genomic grade index . GGI- = ER positive, GGI negative (surrogate for luminal A). TN = triple negative. Her2 + = high expression of Her2. GGI + = ER positive, GGI high (surrogate for luminal B).