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Figure 7 | BMC Medical Genomics

Figure 7

From: A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors

Figure 7

RAS signature distribution across non-small cell lung (A) and breast (B) cancer subsets. The Y-axis shows RAS signature score relative to the mean of all non-small cell lung (A) or breast (B) tumors in the dataset. For (B), GGI = genomic grade index [32]. GGI- = ER positive, GGI negative (surrogate for luminal A). TN = triple negative. Her2 + = high expression of Her2. GGI + = ER positive, GGI high (surrogate for luminal B).

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BMC Medical Genomics

ISSN: 1755-8794

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