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Table 1 The most highly significant functional assignments for the set of smoking correlated genes

From: Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes

Function Annotation

P-value

Number of genes

Cell cytotoxicity

3.7 Ă— 10-10

17

Proliferation of cells

2.1 Ă— 10-9

65

Activation of cells

1.7 Ă— 10-8

31

Cell movement

2.9 Ă— 10-8

35

Lysis of cells

1.2 Ă— 10-7

11

Immune response

2.2 Ă— 10-7

38

Mobilization of calcium

4.0 Ă— 10-7

19

Adhesion of cells

7.8 Ă— 10-7

29

Cell death

1.1 Ă— 10-6

66

Tumorigenesis

1.2 Ă— 10-6

72

Binding of cells

2.9 Ă— 10-6

21

Viral elimination

4.3 Ă— 10-6

3

Cancer

4.9 Ă— 10-6

64

Inflammatory disorder

5.3 Ă— 10-6

44

Cell growth

5.6 Ă— 10-6

50

Cardiovascular disorder of lung

1.4 Ă— 10-4

3

Perturbation of mitochondria

2.7 Ă— 10-4

2

Inflammatory response

3.4 Ă— 10-4

18

Asthma

2.5 Ă— 10-3

9

Free radical scavenging

3.1 Ă— 10-3

8