Figure 3

Intracellular lipid synthesis genes in HAT vs LAT in SC adipose tissue. Gene expression of intracellular lipid synthesis genes (A and B) in SC adipose tissue from LAT (hatched bars) and HAT (solid bars) as assessed by microarray where LAT expression is set at 100%. Correlation in SC adipose tissue from both LAT and HAT subjects between the ASP triad of genes (C3, factor B and adipsin) and (C) DB1 presented for C3 (open circles), FB (solid circles) and adipsin (stars). R values for C3, FB, and FD respectively are (C) 0.548, 0.639, 0.509. (D) Correlations between DGAT2 and GLUT4, R = -0.891. Correlations between GLUT4 and DGAT2 and (E) SCD1 and (F) DGAT1 shown as GLUT4 (solid circles) and DGAT2 (stars). R values (Spearman coefficients) for GLUT4 and DGAT2 respectively are (E) -0.952, 0.903 and (F) -0.964, 0.952. Lines are based on linear regression. Data is expressed as means ± SEM where * p < 0.025, ** p < 0.01 and *** p < 0.001.