Table 2 Methylation Associations
From: Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
Ilmn CpG ID | Gene | Gene Function | Location | coef | exp(coef) | se(coef) | z | Pr(> |z|) | Q value |
|---|---|---|---|---|---|---|---|---|---|
cg01172656 | NRBF2 | Transcription regulation | 10:64563126 | 0.631 | 1.880 | 0.136 | 4.653 | 3.266 × 10-06 | 0.031 |
cg18346038 | PIGU | GPI-anchor biosynthesis | 20:32728489 | 0.624 | 1.867 | 0.136 | 4.603 | 4.164 × 10-06 | 0.031 |
cg00117172 | RUNX3 | Transcription regulation | 1:25128425 | 0.682 | 1.977 | 0.150 | 4.548 | 5.427 × 10-06 | 0.031 |
cg02068676 | COBRA1 | Negative regulation of transcription | 9:139269304 | 0.662 | 1.938 | 0.149 | 4.447 | 8.703 × 10-06 | 0.037 |
cg00025138 | MAP3K9 | Mixed-lineage kinase | 14:70345670 | 0.543 | 1.721 | 0.125 | 4.335 | 1.457 × 10-05 | 0.046 |
cg03221776 | MFSD3 | Transmembrane transport | 8:145704779 | 0.520 | 1.682 | 0.121 | 4.308 | 1.644 × 10-05 | 0.046 |
cg12181621 | HIST1H3I | Nucleosome assembly | 6:27948047 | 0.558 | 1.748 | 0.132 | 4.216 | 2.486 × 10-05 | 0.048 |
cg03752885 | DAPK3 | Induction of apoptosis | 19:3920736 | 0.492 | 1.636 | 0.118 | 4.189 | 2.798 × 10-05 | 0.048 |
cg12688215 | KTI12 | ATP binding | 1:52271816 | 0.446 | 1.563 | 0.107 | 4.175 | 2.976 × 10-05 | 0.048 |
cg07341907 | UNC13B | Exocytosis | 9:35151971 | 0.606 | 1.833 | 0.145 | 4.169 | 3.056 × 10-05 | 0.048 |
cg26850145 | ZBTB5 | Transcription regulation | 9:37455023 | -0.485 | 0.616 | 0.117 | -4.142 | 3.441 × 10-05 | 0.048 |
cg21312090 | TRPS1 | NLS-bearing substrate import into nucleus | 8:116750901 | 0.441 | 1.555 | 0.107 | 4.135 | 3.543 × 10-05 | 0.048 |
cg23266266 | DCUN1D4 | - | 4:52403466 | 0.560 | 1.751 | 0.136 | 4.117 | 3.847 × 10-05 | 0.048 |
cg04466870 | SFXN4 | Transmembrane transport | 10:120915170 | 0.477 | 1.611 | 0.116 | 4.102 | 4.092 × 10-05 | 0.048 |
cg16898420 | PPAPR3 | Catalytic activity | 9:102830899 | -0.711 | 0.491 | 0.175 | -4.066 | 4.786 × 10-05 | 0.048 |
cg17260725 | CCNB2 | Cell division | 15:57184580 | 0.523 | 1.687 | 0.129 | 4.0596 | 4.915 × 10-05 | 0.048 |
cg17428423 | DOC2A | Regulation of calcium ion-dependent exocytosis | 16:29929633 | -0.728 | 0.483 | 0.180 | -4.053 | 5.049 × 10-05 | 0.048 |
cg18731014 | ZNF639 | Transcription regulation | 3:180524284 | 0.556 | 1.744 | 0.137 | 4.050 | 5.122 × 10-05 | 0.048 |
cg21830413 | VPS26 | Protein transport | 10:70554257 | 0.472 | 1.604 | 0.117 | 4.036 | 5.430 × 10-05 | 0.048 |