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Table 2 Methylation Associations

From: Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

Ilmn CpG ID Gene Gene Function Location coef exp(coef) se(coef) z Pr(> |z|) Q value
cg01172656 NRBF2 Transcription regulation 10:64563126 0.631 1.880 0.136 4.653 3.266 × 10-06 0.031
cg18346038 PIGU GPI-anchor biosynthesis 20:32728489 0.624 1.867 0.136 4.603 4.164 × 10-06 0.031
cg00117172 RUNX3 Transcription regulation 1:25128425 0.682 1.977 0.150 4.548 5.427 × 10-06 0.031
cg02068676 COBRA1 Negative regulation of transcription 9:139269304 0.662 1.938 0.149 4.447 8.703 × 10-06 0.037
cg00025138 MAP3K9 Mixed-lineage kinase 14:70345670 0.543 1.721 0.125 4.335 1.457 × 10-05 0.046
cg03221776 MFSD3 Transmembrane transport 8:145704779 0.520 1.682 0.121 4.308 1.644 × 10-05 0.046
cg12181621 HIST1H3I Nucleosome assembly 6:27948047 0.558 1.748 0.132 4.216 2.486 × 10-05 0.048
cg03752885 DAPK3 Induction of apoptosis 19:3920736 0.492 1.636 0.118 4.189 2.798 × 10-05 0.048
cg12688215 KTI12 ATP binding 1:52271816 0.446 1.563 0.107 4.175 2.976 × 10-05 0.048
cg07341907 UNC13B Exocytosis 9:35151971 0.606 1.833 0.145 4.169 3.056 × 10-05 0.048
cg26850145 ZBTB5 Transcription regulation 9:37455023 -0.485 0.616 0.117 -4.142 3.441 × 10-05 0.048
cg21312090 TRPS1 NLS-bearing substrate import into nucleus 8:116750901 0.441 1.555 0.107 4.135 3.543 × 10-05 0.048
cg23266266 DCUN1D4 - 4:52403466 0.560 1.751 0.136 4.117 3.847 × 10-05 0.048
cg04466870 SFXN4 Transmembrane transport 10:120915170 0.477 1.611 0.116 4.102 4.092 × 10-05 0.048
cg16898420 PPAPR3 Catalytic activity 9:102830899 -0.711 0.491 0.175 -4.066 4.786 × 10-05 0.048
cg17260725 CCNB2 Cell division 15:57184580 0.523 1.687 0.129 4.0596 4.915 × 10-05 0.048
cg17428423 DOC2A Regulation of calcium ion-dependent exocytosis 16:29929633 -0.728 0.483 0.180 -4.053 5.049 × 10-05 0.048
cg18731014 ZNF639 Transcription regulation 3:180524284 0.556 1.744 0.137 4.050 5.122 × 10-05 0.048
cg21830413 VPS26 Protein transport 10:70554257 0.472 1.604 0.117 4.036 5.430 × 10-05 0.048
  1. Cox-Regression analysis results of CpGs, with FDR (q value) < 0.05, for time to develop nephropathy. (Location given as Chromosome:Base Pair (Build Hs 36.1))