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Table 1 Clinical and plasma parameters of the study population

From: Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray study

  All individuals Individuals without type 2 diabetes and NASH Type 2 diabetes patients NASH patients Individuals with type 2 diabetes and NASH
  No. of individuals/Mean (SD) Minimal/maximal values No. of individuals/Mean (SD) Minimal/maximal values No. of individuals/Mean (SD) Minimal/maximal values No. of individuals/Mean (SD) Minimal/maximal values No. of individuals/Mean (SD) Minimal/maximal values
Number of individuals 75   29   25   41   20  
Male/female 22/53   7/22   7/18   12/29   4/16  
Age (years) 44.4 (9.9) 17 - 67 40.3 (9.2) 17 - 54 48.2 (9.4) 28 - 67 45.8 (8.9) 28 - 65 46.5 (8.1) 28 - 65
BMI (kg/m2) 46.5 (9.6) 34.6 - 73.6 42.6 (6.5) 34.6 - 56.8 49.4 (11.4) 34.8 - 73.6 48.7 (10.8) 34.8 - 73.6 49.6 (12.1) 34.8 - 73.6
Glucose (mmol/l) 6.60 (2.1) 4.3 - 14.5 5.53 (0.49) 4.3 - 6.5 8.73 (2.5) 4.3 - 14.5 7.16 (2.56) 4.3 - 14.5 8.8 (2.72) 4.3 - 14.5
Insulin (mU/l) 19.3 (10.9) 3.8 - 53 16.7 (8.8) 5.6 - 37 20.6 (13.1) 5.5 - 53 20.9 (11.1) 3.8 - 49 20.4 (10.9) 3.8 - 49
HbA1c 6.58 (1.39) 5.1 - 12.1 6 (0.54) 5.1 - 7.2 7.9 (1.78) 5.3 - 12.1 6.88 (1.65) 5.2 - 12.1 7.85 (1.88) 5.2 - 12.1
Total cholesterol (mmol/l) 5.08 (1.1) 3 - 9.8 4.93 (0.65) 3.5 - 6.1 5.15 (1.43) 3.5 - 9.8 5.08 (1.23) 3 - 9.8 5.2 (1.5) 3 - 9.8
HDL cholesterol (mmol/l) 0.98 (0.38) 0.5 - 2.8 1.05 (0.3) 0.6 - 1.9 0.8 (0.23) 0.5 - 1.3 0.93 (0.44) 0.5 - 2.8 0.78 (0.22) 0.5 - 2.8
LDL cholesterol (mmol/l) 3.22 (1.02) 1.1 - 7.4 3.16 (0.86) 1.1 - 4.3 3.29 (1.18) 1.5 - 7.4 3.17 (1.06) 1.5 - 7.4 3.32 (1.25) 1.5 - 7.4
TG (mmol/l) 2.26 (2.12) 0.63 - 16.4 1.67 (0.95) 0.63 - 4.2 3.31 (3.46) 0.88 - 16.4 2.73 (2.71) 0.88 - 16.4 3.56 (3.67) 0.88 - 16.4
NEFA (mmol/l) 0.64 (0.32) 0.12 - 1.66 0.52 (0.34) 0.12 - 1.66 0.72 (0.3) 0.16 - 1.33 0.71 (0.28) 0.21 - 1.33 0.76 (0.29) 0.21 - 1.33
ALAT (U/l) 25.7 (16.5) 6 - 124 19.8 (6.3) 7 - 37 32.3 (23.1) 10 - 124 27.7 (19.3) 6 - 124 32.4 (24.8) 6 - 124
ASAT (U/l) 25.3 (12.9) 7 - 72 21.1 (11.6) 7 - 50 28.9 (15.4) 8 - 72 28.4 (13) 8 - 72 30.7 (16) 8 - 72
CRP (mg/l) 10.2 (8.5) 1 - 37 9.9 (9.2) 1 - 37 13.1 (10) 1.7 - 35 10 (8.2) 1.7 - 35 12.8 (10.2) 1.7 - 35
  1. Data are means ± standard deviation (SD) and the minimal and maximal values for each trait. Data are given for all individuals, individuals without type 2 diabetes or NASH, type 2 diabetes patients, NASH patients, and individuals with both type 2 diabetes and NASH. Patients with type 2 diabetes are 36, 37, 40, 42, 43, 49, 51, 54, 55, 57, 60, 63, 64, 65, 69, 75, 77, 78, 79, 85, 87, 97, 101, 103, and 110 - IDs are concordant with the IDs used submitted to the Gene Expression Omnibus database. Patients with NASH are 38, 42, 43, 44, 45, 47, 49, 51, 52, 53, 54, 57, 58, 60, 62, 63, 64, 65, 69, 72, 75, 78, 79, 83, 85, 87, 88, 92, 93, 95, 97, 99, 100, 101, 102, 103, 104, 105, 107, 110, and 113. TG, triglycerides; NEFA, non-esterified fatty acid; ALAT, alanine aminotransaminase; ASAT, aspartate aminotransaminase; CRP, C-reactive protein; NASH, non-alcoholic steatohepatitis.