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Table 2 Overlap between genes in the 10 largest modules identified in subcutaneous (SAT) and visceral adipose tissue (VAT)

From: Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray study

  

SAT 1

SAT 2

SAT 3

SAT 4

SAT 5

SAT 6

SAT 7

SAT 8

SAT 9

SAT 10

 

Total

723

554

344

308

146

75

87

87

103

46

VAT 1

469

20

1

27

2

*5 69

*6 29

0

0

0

0

VAT 2

641

*1 536

3

12

1

1

7

0

0

8

1

VAT 3

524

9

*2 307

1

7

0

0

0

0

31

0

VAT 4

464

5

2

2

16

5

1

*7 27

3

0

0

VAT 5

306

1

63

0

*4 56

0

0

0

4

4

0

VAT 6

253

6

0

*3 115

1

1

0

0

0

0

0

VAT 7

193

5

0

32

0

6

0

0

0

0

1

VAT 8

209

27

23

1

0

0

0

0

0

*9 58

0

VAT 9

103

0

0

0

32

0

0

1

*8 54

0

0

VAT 10

104

0

60

0

1

0

0

0

0

5

0

  1. After generation of modules in both types of adipose tissue, the overlap in gene content of the 10 largest modules in VAT and SAT was determined. As an example, modules VAT 2 and SAT 1 are largely the same since approximately 75% of the genes present in one of these modules is also present in the other. For most, although not all, of the modules in one adipose tissue there is a similar module in the other adipose tissue. P-values to determine the significance of the overlap between the modules were performed using a Fisher's exact test: *1: p = 1.54 × 10-321; *2: p = 1.20 × 10-321; *3: p = 2.07 × 10-138; *4: p = 1.58 × 10-43; *5: p = 5.74 × 10-73; *6: p = 6.65 × 10-28; *7: p = 3.33 × 10-23; *8: p = 2.16 × 10-107; *9: p = 1.33 × 10-89. Genes within module SAT 10 overlap with genes within module VAT 11 (not shown).