Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray study

Table 3 Modules correlated with metabolic traits in subcutaneous (SAT) and visceral adipose tissue (VAT)

Tissue	Module ID	Correlated trait	No. of genes in module	Correlation coefficient	P-value
SAT	31	Gender	14		6.6 × 10^-66
	4	HDL cholesterol	308	-0.58	2.5 × 10^-7
	13	Glucose	28	-0.51	7.0 × 10^-6
		Triglycerides		-0.50	1.8 × 10^-5
	8	HDL cholesterol	87	-0.49	2.7 × 10^-5
	39	HDL cholesterol	7	-0.49	3.0 × 10^-5
VAT	31	Gender	14		8.2 × 10^-60
	40	Insulin	12	-0.54	4.3 × 10^-6
		BMI		-0.49	2.8 × 10^-5
	9	Glucose	103	0.50	2.1 × 10^-5

Only those modules significantly correlated to a metabolic trait after Bonferroni correction are shown, with the names of the modules, the traits to which they were correlated, the number of genes that comprise the module, and the Spearman rank correlation coefficient between the value of the module - i.e. the average of all the probes in the module - and the trait. To calculate p-values for association between a module and gender we used a students T-test.

ISSN: 1755-8794