Table 4 Over-represented Panther biological processes in modules correlated to a metabolic trait in subcutaneous (SAT) and visceral adipose tissue (VAT)
| Â | SAT Module 4 | SAT Module 8 | VAT Module 9 | |||
|---|---|---|---|---|---|---|
| Â | No. of genes in module | P-value | No. of genes in module | P-value | No. of genes in module | P-value |
Total | 308 | Â | 87 | Â | 103 | Â |
Signal transduction | 67 | 2.8 × 10-4 | NA | NS | NA | NS |
- Intracellular signalling cascade | 26 | 2.0 × 10-3 | NA | NS | NA | NS |
Immunity and defense | 43 | 3.5 × 10-9 | 31 | 4.1 × 10-17 | 21 | 8.2 × 10-7 |
- T-cell-mediated immunity | 13 | 9.2 × 10-5 | 7 | 6.4 × 10-4 | NA | NS |
- MHCII-mediated immunity | NA | NS | 5 | 2.5 × 10-5 | NA | NS |
- Macrophage-mediated immunity | NA | NS | 7 | 7.5 × 10-5 | 5 | 3.3 × 10-2 |
- Endocytosis | NA | NS | 7 | 6.2 × 10-3 | NA | NS |
- B-cell and antibody-mediated immunity | 7 | 2.4 × 10-2 | 4 | 4.9 × 10-2 | NA | NS |
- Complement mediated immunity | NA | NS | 4 | 2.4 × 10-3 | NA | NS |
Transport | 41 | 2.8 × 10-7 | NA | NS | 16 | 1.2 × 10-3 |
- Ion transport | 23 | 1.8 × 10-4 | NA | NS | NA | NS |
Cell adhesion | 20 | 1.6 × 10-3 | NA | NS | 11 | 9.2 × 10-4 |
Lipid, fatty acid and steroid metabolism | 21 | 9.7 × 10-3 | NA | NS | NA | NS |
Carbohydrate metabolism | 19 | 2.5 × 10-3 | NA | NS | NA | NS |
Other | 89 | NA | 37 | NA | 44 | NA |
Unclassified | 76 | NA | 19 | NA | 24 | NA |