Degradation of RNA. The effect of degradation time on calculated RNA Integrity Numbers (RINs) for the given samples P159, P160 and P162 is shown. (A) Bioanalyzer profiles of total RNA for degradation levels used in the microarray study (control, 1:45 h, 2:30 h, 3:15 h). RINs are shown next to each total RNA profile. (B) RIN-dependence of degradation time separately for all patients. An additional time point (240 Min/4:00 h) without gene expression profile is also present.