20 Genes up-regulated following 17AAG treatment | |||
---|---|---|---|
Gene name | Description | FDR | Fold Change |
CHORDC1 | Cysteine and histidine-rich domain (CHORD)-containing 1 (CHORDC1) | 0.011 | 3.9 |
DEDD2 | Death effector domain containing 2 (DEDD2) | 0.011 | 2.2 |
HSPA8 | Heat shock 70kDa protein 8 (HSPA8) transcript variant 1 | 0.011 | 4.6 |
NUDT9 | Nudix (nucleoside diphosphate linked moiety X)-type motif 9 (NUDT9). transcript variant 1 | 0.011 | 2.4 |
PRDM11 | PR domain containing 11 (PRDM11) | 0.011 | 2.8 |
UBE2C | Ubiquitin-conjugating enzyme E2C (UBE2C) | 0.011 | 2.4 |
ZFP95 | Zinc finger protein 95 homolog (mouse) (ZFP95). transcript variant 1 | 0.02 | 1.5 |
ZNF587 | Zinc finger protein 587 (ZNF587) transcript variant 1 | 0.025 | 2.8 |
RGS2 | Regulator of G-protein signalling 2. 24kDa (RGS2) | 0.03 | 4.8 |
CR2 | CR2/CD21/C3d/Epstein-Barr virus receptor mRNA. complete cds. [M26004] | 0.034 | 2.5 |
DNAJA1 | DnaJ (Hsp40) homolog. subfamily A. member 1 (DNAJA1) | 0.034 | 3.3 |
HSPA1L | Heat shock 70kDa protein 1-like (HSPA1L) | 0.034 | 3.1 |
MICB | MHC class I polypeptide-related sequence B (MICB) | 0.034 | 1.4 |
RACGAP1 | Rac GTPase activating protein 1 (RACGAP1) | 0.034 | 2.1 |
ZNF473 | Zinc finger protein 473 (ZNF473). transcript variant 1 | 0.034 | 1.7 |
DNAJB12 | DnaJ (Hsp40) homolog. subfamily B. member 12 (DNAJB12). transcript variant 1 | 0.035 | 1.6 |
HSP90AA1 | Heat shock protein 90kDa alpha (cytosolic). class A member 1 (HSP90AA1) transcript variant 2 | 0.045 | 5.3 |
PPARBP | PPAR binding protein. mRNA (cDNA clone IMAGE:4822636). complete cds. [BC060758] | 0.045 | 1.7 |
CCDC12 | Coiled-coil domain containing 12 (CCDC12) | 0.046 | 1.8 |
HSPA4L | Heat shock 70kDa protein 4-like (HSPA4L) | 0.046 | 3.6 |
15 Genes down-regulated following 17AAG treatment | |||
Gene name | Description | FDR | Fold Change |
PLK3 | Polo-like kinase 3 (Drosophila) (PLK3) | 0.025 | 5.8 |
TMEM129 | Transmembrane protein 129 (TMEM129) | 0.027 | 2.2 |
IER3 | Immediate early response 3 (IER3). transcript variant short | 0.032 | 8.7 |
CCND1 | Cyclin D1 (CCND1) | 0.034 | 5.5 |
JUNB | Jun B proto-oncogene (JUNB) | 0.034 | 5 |
TSEN2 | tRNA splicing endonuclease 2 homolog (S. cerevisiae) (TSEN2) | 0.034 | 2.8 |
CCDC85B | Coiled-coil domain containing 85B (CCDC85B) | 0.035 | 2.3 |
WDR4 | WD repeat domain 4 (WDR4). transcript variant 2 | 0.035 | 2.5 |
RFC4 | Replication factor C (activator 1) 4. 37kDa (RFC4). transcript variant 1 | 0.044 | 2.2 |
PYCRL | Pyrroline-5-carboxylate reductase-like (PYCRL) | 0.045 | 2.9 |
SHMT2 | Serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2) | 0.045 | 1.7 |
C6orf203 | Chromosome 6 open reading frame 203 (C6orf203) | 0.046 | 2.2 |
MAN1B1 | Mannosidase. alpha. class 1B. member 1 (MAN1B1) | 0.046 | 2.2 |
NFKBIA | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor. alpha (NFKBIA) | 0.047 | 4.2 |
SFT2D3 | SFT2 domain containing 3 (SFT2D3) | 0.047 | 1.9 |