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Table 1 Clinical characteristics of patients

From: Hepatic microRNA expression is associated with the response to interferon treatment of chronic hepatitis C

Characteristics SVR (n = 46) R (n = 28) NR (n = 25) p-value
Age (years) 57.0 ± 9.8 61.2 ± 8.3 60.6 ± 7.6 0.09†
Male (%) 28 (61%) 11 (39%) 9 (36%) 0.08§
Weight (kg) 59.5 ± 9.0 56.6 ± 9.9 56.0 ± 7.7 0.13†
HCV RNA (×106 copies/ml) 1.90 ± 1.95 1.83 ± 1.04 1.58 ± 0.93 0.62†
Fibrosis stage     
F 0 1 1 1 0.50§
F 1 29 16 10  
F 2 10 7 6  
F 3 6 4 7  
F 4 0 0 1  
WBC(×103/mm3) 5.31 ± 1.59 5.18 ± 1.24 4.71 ± 1.15 0.29†
Hemoglobin (g/dl) 14.2 ± 1.26 13.6 ± 1.35 13.5 ± 1.13 0.022†
Platelet (×104/mm3) 16.7 ± 5.0 16.4 ± 4.0 15.2 ± 6.1 0.25†
AST (IU/L) 54.8 ± 48.1 46.6 ± 29.3 57.0 ± 28.5 0.17†
ALT (IU/L) 74.5 ± 87.8 47.9 ± 28.6 67.6 ± 43.2 0.15†
γGTP (IU/L) 56.0 ± 69.4 38.5 ± 28.9 74.3 ± 59.0 0.025†
ALP (IU/L) 248 ± 71.5 245 ± 75.7 323 ± 151 0.038†
Total Bilirubin (mg/dl) 0.67 ± 0.22 0.72 ± 0.30 0.68 ± 0.19 0.95†
Albumin (g/dl) 4.21 ± 0.31 4.13 ± 0.27 4.01 ± 0.48 0.14†
  1. Abbreviations. SVR, sustained virological response; R, relapse; NR, non responder; Differences in clinical characteristics among three groups were tested using †Kruskal-Wallis test, or §Fisher's exact test. AST, aspartate aminotransferase; ALT, alanine aminotransferase; WBC, white blood cell; ALP, alkaline phosphatase; γGTP, gamma-glutamyl transpeptidase.