Skip to main content

Table 1 Clinical characteristics of patients

From: Hepatic microRNA expression is associated with the response to interferon treatment of chronic hepatitis C

Characteristics

SVR (n = 46)

R (n = 28)

NR (n = 25)

p-value

Age (years)

57.0 ± 9.8

61.2 ± 8.3

60.6 ± 7.6

0.09†

Male (%)

28 (61%)

11 (39%)

9 (36%)

0.08§

Weight (kg)

59.5 ± 9.0

56.6 ± 9.9

56.0 ± 7.7

0.13†

HCV RNA (×106 copies/ml)

1.90 ± 1.95

1.83 ± 1.04

1.58 ± 0.93

0.62†

Fibrosis stage

    

F 0

1

1

1

0.50§

F 1

29

16

10

 

F 2

10

7

6

 

F 3

6

4

7

 

F 4

0

0

1

 

WBC(×103/mm3)

5.31 ± 1.59

5.18 ± 1.24

4.71 ± 1.15

0.29†

Hemoglobin (g/dl)

14.2 ± 1.26

13.6 ± 1.35

13.5 ± 1.13

0.022†

Platelet (×104/mm3)

16.7 ± 5.0

16.4 ± 4.0

15.2 ± 6.1

0.25†

AST (IU/L)

54.8 ± 48.1

46.6 ± 29.3

57.0 ± 28.5

0.17†

ALT (IU/L)

74.5 ± 87.8

47.9 ± 28.6

67.6 ± 43.2

0.15†

γGTP (IU/L)

56.0 ± 69.4

38.5 ± 28.9

74.3 ± 59.0

0.025†

ALP (IU/L)

248 ± 71.5

245 ± 75.7

323 ± 151

0.038†

Total Bilirubin (mg/dl)

0.67 ± 0.22

0.72 ± 0.30

0.68 ± 0.19

0.95†

Albumin (g/dl)

4.21 ± 0.31

4.13 ± 0.27

4.01 ± 0.48

0.14†

  1. Abbreviations. SVR, sustained virological response; R, relapse; NR, non responder; Differences in clinical characteristics among three groups were tested using †Kruskal-Wallis test, or §Fisher's exact test. AST, aspartate aminotransferase; ALT, alanine aminotransferase; WBC, white blood cell; ALP, alkaline phosphatase; γGTP, gamma-glutamyl transpeptidase.