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Table 4 Extracted miRNA related to the final outcome of combination therapy

From: Hepatic microRNA expression is associated with the response to interferon treatment of chronic hepatitis C

Gene Name

Fold Change (NR/SVR)

p-value with FDR correction

p-value without correction

hsa-miR-34b*

1.50

3.53E-02

6.95E-05

hsa-miR-145

1.35

3.55E-02

5.50E-05

hsa-miR-143

1.31

4.65E-02

6.46E-04

hsa-miR-652

1.28

4.33E-02

3.43E-04

hsa-miR-18a

1.22

4.33E-02

2.02E-05

hsa-miR-27b

0.78

4.33E-02

3.97E-05

hsa-miR-422b*

0.71

4.33E-02

1.44E-04

hsa-miR-378

0.70

4.86E-02

1.38E-03

hsa-miR-122

0.72

> 5.00E-02

2.59E-04

Gene Name

Fold Change (NR/R)

p-value with FDR correction

p-value without correction

hsa-miR-148a

0.59

1.60E-02

8.99E-04

has-miR-122

0.72

> 5.00E-02

6.23E-04

Gene Name

Fold Change (R/SVR)

P-value

p-value without correction

hsa-let-7a

1.15

3.93E-02

1.94E-03

hsa-let-7f

1.24

1.04E-02

3.60E-03

hsa-let-7g

1.17

1.93E-02

1.82E-02

hsa-miR-100

1.23

1.93E-02

9.23E-04

hsa-miR-10a

1.37

1.26E-02

2.40E-03

hsa-miR-126

1.36

1.04E-02

1.50E-03

hsa-miR-21

1.30

4.78E-02

3.45E-02

hsa-miR-335

2.00

2.83E-02

3.50E-02

hsa-miR-370

0.36

1.38E-02

2.96E-03

hsa-miR-494

0.37

3.93E-02

1.97E-03

hsa-miR-590

1.26

3.93E-02

5.59E-03

hsa-miR-98

1.22

1.38E-02

6.64E-03

  1. Asterisk was denoted the common miRNAs appeared whose expression level between NR and SVR, and nonEVR and cEVR.