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Table 1 Top 10 most frequent ROS-diabetes targets

From: Literature-based discovery of diabetes- and ROS-related targets

Symbol

Name

#Paper

Match Strings

INS

insulin

503

INS | insulin | proinsulin |

SOD1

superoxide dismutase 1

368

Sod1 | SOD1 | SOD1 | *

CAT

catalase

241

CAT | catalase | *

PRKCA

protein kinase C, alpha

194

PKCA | PKC-alpha | *

ALB

albumin

179

albumin | serum albumin |

NOX5

NADPH oxidase 5

177

NOX5 | nadph oxidase |

NOS2A

nitric oxide synthase 2A

144

NOS | iNOS | Nos2 |*

XDH

xanthine dehydrogenase

133

XOR |xanthine dehydrogenase| *

AGT

angiotensinogen

131

Ang-II | ANG | AGT | AngI | *

TNF

tumor necrosis factor

120

TNFA | TNF | TNF-alpha | *

  1. * Matching strings are truncated to fit in the table. The full contents are available in the Additional File 2. '#Paper' refers to the number of documents in which each target was mentioned at least once.