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Table 2 Overview of results of multivariate analysis (PLS-DA) of various data sets.

From: Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study

 

Original data set

After variable selection

 

# variables

error rate

# variables

error rate

plasma proteomics

66

21%

46

10%

plasma oxylipids

30

26%

19

10.5%

plasma GC-MS

137

42%

-

-

plasma LC-MS polar

130

53%

  

plasma LC-MS lipids

61

37%

-

-

plasma LC-MS free fatty acids

14

37%

-

-

PBMC transcriptomics

-

-

3355

0%

  1. All data sets were analyzed for differences between diclofenac and placebo treatment by PLS-DA. The results of the different multivariate models are expressed as error rates. Only when the error rate for the original data set was < = 30%, analysis was continued by variable selection, as described in the materials and methods section.
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BMC Medical Genomics

ISSN: 1755-8794

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