Figure 6
Western blot analysis of RelB in CLL patients. The expression of RelB is higher in resistant CLLs in females (RF) (n = 6, 21.2 ± 15.5) than in resistant CLL in males (RM) (4.2 ± 4.8, n = 10), U test p = 0.0048; higher also in resistant females (RF) (n = 6, 21.2 ± 15.5) vs. sensitive females (SF) (6.2 ± 5.5, n = 7), U test p = 0.0184; higher in sensitive males (SM) (12.2 ± 8.0, n = 7) compared with resistant males (RM) (4.2 ± 4.8, n = 10), U test p = 0.0147; but no different between sensitive males (SM, n = 7) and sensitive females (SF, n = 9). Results are shown using box-plots with medians (lines inside boxes), 25th and 75th percentiles (limits of boxes), and the 10th and 90th percentiles (whiskers). (▼) indicates an outlier. RELB values are given as arbitrary units after normalization with β-actin. Representative images of Western blots are shown under the graphs.