Figure 2

Allele frequency distributions for null expectations. Allele frequencies are binned into 0.10 intervals. Derived probabilities are labelled in black and ancestral probabilities are labelled in grey. Neutral expectations use a polymorphism threshold (d) of 0.025. A) Allele frequency distributions for HapMap alleles prior to detection (n = 1000). B) Allele frequency distributions for HapMap alleles after weighting by the probability of detection (n = 1000). C) Theoretical allele frequency distributions for neutral alleles prior to detection. D) Theoretical allele frequency distributions for neutral alleles after weighting by the probability of detection.