Table 1 Clinicopathological characteristics of 20 breast tumors.
Characteristic | Total N = 20 | % | HER2+ N = 9 (%) | HER2- N = 11 (%) |
|---|---|---|---|---|
Median age (range) | 58.5 (35, 76) | 57 (35, 73) | 59 (38, 76) | |
Age Group: | ||||
< 40 | 3 | 15 | 2 (22) | 1 (9) |
40-49 | 2 | 10 | 1 (11) | 1 (9) |
50-59 | 6 | 30 | 2 (22) | 4 (36) |
≥ 60 | 9 | 45 | 4 (44) | 5 (46) |
Initial HER2 Status: | ||||
0 | 6 | 30 | ||
1 + | 1 | 5 | NA | NA |
2 + | 0 | 0 | ||
3 + | 13 | 65 | ||
Hercept Test HER2 Status: | ||||
0 | 4 | 20 | ||
1 + | 7 | 35 | NA | NA |
2 + | 2 | 10 | ||
3 + | 7 | 35 | ||
Estrogen Status: | ||||
Positive | 20 | 100 | 9 (100) | 11 (100) |
30% ER+ cells | 0 (0) | 0 (9) | ||
70% ER+ cells | 1 (11) | 0 (0) | ||
80% ER+ cells | 2 (22) | 1 (9) | ||
90% ER+ cells | 2 (22) | 4 (36) | ||
95% ER+ cells | 2 (22) | 2 (18) | ||
100% ER+ cells | 2 (22) | 2 (18) | ||
% cell not recorded | 0 (0) | 0 (0) | ||
Negative | 0 | 0 | ||
Progesterone Status: | ||||
Positive | 19 | 95 | 9 (100) | 10 (91) |
Negative | 1 | 5 | 0 (0) | 1 (9) |
Nodes Positive: | ||||
1-3 | 10 | 50 | 5 (56) | 5 (46) |
4-9 | 6 | 30 | 2 (22) | 4 (36) |
≥ 10 | 4 | 20 | 2 (22) | 2 (18) |
Predominant Tumor Histology: | ||||
Ductal | 20 | 100 | 9 (100) | 11 (100) |
Lobular | 0 | |||
Nottingham Grade: | ||||
2 | 11 | 55 | 4 (44) | 8 (73) |
3 | 9 | 45 | 5 (56) | 3 (27) |
Stage: | ||||
2 | 12 | 60 | 5 (56) | 7 (64) |
3 | 8 | 40 | 4 (44) | 4 (36) |
Pathologic Tumor Size: | ||||
< 2 cm | 5 | 25 | 3 (33) | 2 (18) |
≥ 2 cm | 15 | 75 | 6 (67) | 9 (82) |
Year of Block Procurement: | ||||
1998-2000 | 3 | 15 | 22 (22) | 1 (9) |
2001-2003 | 11 | 55 | 4 (44) | 7 (64) |
2004-2006 | 6 | 30 | 3 (33) | 3 (27) |