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Table 1 Clinicopathological characteristics of 20 breast tumors.

From: Expression profiling of formalin-fixed paraffin-embedded primary breast tumors using cancer-specific and whole genome gene panels on the DASL®platform

Characteristic Total N = 20 % HER2+ N = 9 (%) HER2- N = 11 (%)
Median age (range) 58.5 (35, 76)   57 (35, 73) 59 (38, 76)
Age Group:     
< 40 3 15 2 (22) 1 (9)
40-49 2 10 1 (11) 1 (9)
50-59 6 30 2 (22) 4 (36)
≥ 60 9 45 4 (44) 5 (46)
Initial HER2 Status:     
0 6 30   
1 + 1 5 NA NA
2 + 0 0   
3 + 13 65   
Hercept Test HER2 Status:     
0 4 20   
1 + 7 35 NA NA
2 + 2 10   
3 + 7 35   
Estrogen Status:     
Positive 20 100 9 (100) 11 (100)
30% ER+ cells    0 (0) 0 (9)
70% ER+ cells    1 (11) 0 (0)
80% ER+ cells    2 (22) 1 (9)
90% ER+ cells    2 (22) 4 (36)
95% ER+ cells    2 (22) 2 (18)
100% ER+ cells    2 (22) 2 (18)
% cell not recorded    0 (0) 0 (0)
Negative 0 0   
Progesterone Status:     
Positive 19 95 9 (100) 10 (91)
Negative 1 5 0 (0) 1 (9)
Nodes Positive:     
1-3 10 50 5 (56) 5 (46)
4-9 6 30 2 (22) 4 (36)
≥ 10 4 20 2 (22) 2 (18)
Predominant Tumor Histology:     
Ductal 20 100 9 (100) 11 (100)
Lobular 0    
Nottingham Grade:     
2 11 55 4 (44) 8 (73)
3 9 45 5 (56) 3 (27)
Stage:     
2 12 60 5 (56) 7 (64)
3 8 40 4 (44) 4 (36)
Pathologic Tumor Size:     
< 2 cm 5 25 3 (33) 2 (18)
≥ 2 cm 15 75 6 (67) 9 (82)
Year of Block Procurement:     
1998-2000 3 15 22 (22) 1 (9)
2001-2003 11 55 4 (44) 7 (64)
2004-2006 6 30 3 (33) 3 (27)
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