Expression patterns of the SLC45A3-ELK4 e4-e2 TIC and related genes. (A) qRT-PCR levels of SLC45A3-ELK4 e4-e2 TIC in the sequenced prostate tumor and normal sample pairs T1/N1, T2/N2, and T3/N3 pairs (labeled as 1-3, and marked with "-" for ERG-negative and "+" for ERG-positive status), plus panels of 6 ERG-negative and 14 ERG-positive prostate tumor and normal matched samples, a commercial sample of prostate normal RNA, and 9 lung cancer cell lines. (B) Microarray-based expression profile of SLC45A3 (Affymetrix probe 228696-at on GeneChip HG-U133B) across human tissues, showing prostate specificity. Samples are organized by tissue, with normal samples above (green) and cancer samples below (red). (C) Microarray-based expression profile of ELK4 (Affymetrix probe 206919-at on GeneChip HG-U133A). (D) Relationship of SLC45A3 and ERG (Affymetrix probe set 241926-s-at on GeneChip HG-U133B) expression levels in prostate tumor and normal samples, showing that highest expression of SLC45A3 is restricted to samples with low expression of ERG.