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Figure 1 | BMC Medical Genomics

Figure 1

From: Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines

Figure 1

Categorization of cell lines in the NCI60 panel into paclitaxel sensitive and resistant groups. This graph was generated by SAS 9.1 and shows the distribution of the panel's response data to paclitaxel after a non-parametric kernel estimation with bandwidth of 0.55 was applied. The 62 cell lines which had drug response data available from DTP were used in this categorization. Normalized drug response z-scores are listed on the x-axis and relative frequency in each bin on the y-axis. The vertical line indicates the location of the antimode in the distribution and the z-score value (1.2) which determined whether cell lines were categorized as sensitive or resistant.

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BMC Medical Genomics

ISSN: 1755-8794

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