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Table 3 Plasma proteins of which absolute levels significantly changed due to extended fasting (36 h) compared with overnight fasting (12 h), as assessed using the multiplex immunoassay (RBM)

From: 2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

Protein Accession # Fold-change p-value Adjusted p-value
IGF-1 P01343 -2.72 <0.001 <0.001
Leptin P41159 -2.59 <0.001 <0.001
Erythropoietin P01588 -1.56 0.080 0.187
IgE n.a. -1.54 0.002 0.013
IL-8 P10145 -1.51 <0.001 0.001
MMP-3 P08254 -1.48 <0.001 <0.001
Thyroid Stimulating Hormone P01222 -1.47 <0.001 <0.001
Insulin P01308 -1.29 <0.001 0.001
Carcinoembryonic Antigen P06731 -1.29 0.037 0.116
IL-1beta P01584 -1.19 <0.001 <0.001
PAI-1 P05121 -1.19 0.002 0.013
Apolipoprotein A-1 (ApoA1) P02647 -1.18 0.006 0.025
MCP-1 P13500 -1.17 <0.001 0.001
Eotaxin P51671 -1.16 0.001 0.005
VEGF P15692 -1.14 <0.001 <0.001
IL-16 Q14005 -1.13 <0.001 0.002
EGF P01133 -1.12 0.085 0.190
IL-18 Q14116 -1.12 0.013 0.048
Alpha-Fetoprotein P02771 -1.12 <0.001 <0.001
Fatty Acid Binding Protein P05413 -1.07 0.006 0.025
IgA n.a. -1.07 0.043 0.116
Factor VII (F7) P08709 -1.06 0.061 0.157
Creatine Kinase-MB P06732 -1.04 0.075 0.181
IL-10 P22301 -1.04 0.041 0.116
Glutathione S-Transferase P09211 -1.04 0.010 0.041
Tissue Factor (TF) P13726 -1.03 0.004 0.019
Prostatic Acid Phosphatase P15309 -1.03 0.018 0.067
Alpha-2 Macroglobulin (A2M) P01023 1.02 0.021 0.072
Complement 3 P01024 1.02 0.028 0.092
TIMP-1 P01033 1.02 0.005 0.025
IL-12p70 P29459 1.03 0.038 0.116
VCAM-1 P19320 1.05 0.011 0.044
Serum Amyloid P (SAP) P02743 1.07 0.072 0.179
Lipoprotein (a) P08519 1.09 0.041 0.116
MIP-1beta P13236 1.09 0.048 0.127
TNF-alpha P01375 1.10 0.042 0.116
EN-RAGE P80511 1.17 0.085 0.190
Ferritin P02794 1.27 <0.001 0.001
C Reactive Protein (CRP) P02741 1.55 <0.001 0.002
  1. n.a. = no accession #