Discriminating lymphomas and reactive lymphadenopathy in lymph node biopsies by gene expression profiling

BMC Medical Genomics

Table 6 The top 20 annotated classifier genes of DLBCL.

Accession number	Gene name	Symbol	Fold change
NM_000439	Proprotein convertase subtilisin/kexin type 1	RBM16	2.03
AF111846	Transcribed locus	CCNB1	1.54
NM_000492	Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	TFRC	0.66
NM_017421	Coenzyme Q3 homolog, methyltransferase (S. cerevisiae)	SLC25A4	0.65
AL137452	Protein arginine methyltransferase 10 (putative)	PGD	0.63
NM_016138	Coenzyme Q7 homolog, ubiquinone (yeast)	CDKN3	0.63
NM_014726	TBK1 binding protein 1	CCT8	0.63
AL049705	Mitochondrial ribosomal protein S14	FKBP4	0.61
NM_018320	Ring finger protein 121	BZW2	0.61
NM_003566	Early endosome antigen 1	CCT3	0.60
NM_006231	Polymerase (DNA directed), epsilon	GMPS	0.56
NM_015902	Ubiquitin protein ligase E3 component n-recognin 5	MSI1	0.56
NM_002626	Phosphofructokinase, liver	MMRN1	0.55
NM_001634	Adenosylmethionine decarboxylase 1	SLMAP	0.55
NM_006476	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G	NDUFV1	0.53
NM_007159	Sarcolemma associated protein	SBNO1	0.53
NM_006330	Lysophospholipase I	ESPL1	0.51
NM_003384	Vaccinia related kinase 1	MYO19	0.49
NM_006585	Chaperonin containing TCP1, subunit 8 (theta)	CYC1	0.47
NM_001151	Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	ANAPC5	0.47

Genes are ranked from high to low fold change (differential expression in DLBCL versus remainder of samples).

ISSN: 1755-8794