Figure 1

Heterogeneous distribution of genes in immune databases and an incomplete catalogue of immune knowledge. (A) Bar chart depicting the shared gene distribution of the immune resources. 82 of the total integrated set of 4833 genes are common to all 6 manually curate resources (orange colored bar). Few genes were unique to an individual database, ranging from a minimum of two for "Immunome" and 122 for the "Innate". (B) An approximation using a Venn Euler diagram illustrates the heterogeneous overlap among the different databases. The Innate database being the largest resource has the largest intersections. The septic shock resource has smaller overlaps with the others (with the exception of Innate) highlighting its focus on collating genes related to the response to bacterial toxins during septic shock.