Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study

Table 2 Number of genes differentially expressed between HT users and non-users (in the Limma analysis)

HT type	Total sample N	Single users¹ N	Number of genes FDR <0.25
HT all types	52	23	5(9)²
E₂ or E₂/P systemic	32	15	33
E₂ systemic	9	7	10
Tibolone	10	2	400
Tibolone2³	10	10	0(58)³
Thyroxine	20	5	8
Non-users	98	98

¹ Users of other medication excluded.
² FDR <0.28, 5 genes with FDR <0.25
³ All tibolone users were included in the analysis; there were 58 genes with FDR <0.50

ISSN: 1755-8794