DWD Integration. The effect of DWD on the first two principal components (PC) and hierarchical clustering of the data. DWD was able to remove the separation between the datasets as indicated by the PC-plots and by the mixing of the branches in the dendrogram. The PC plots show that biological information is preserved after DWD integration (Samples cluster by dataset before integration and by tumor entity thereafter). Leaves in the dendrogram are colored by tumor entity and branches are colored by dataset.