Figure 2From: Identification of SERPINA1 as single marker for papillary thyroid carcinoma through microarray meta analysis and quantification of its discriminatory power in independent validation Heatmap and hierarchical clustering of meta analysis data on further candidate marker genes. As shown in the heatmap, there are a range of different genes with good discriminatory power between PTC and benign nodules. Therefore, removing SERPINA1 from the meta analysis dataset leads to a range of possible expression signatures with 99% classification accuracy in leave-one-out crossvalidation (see main text). In all cases, the same one sample is misclassified (see discussion for details). Columns correspond to samples and rows to genes, the red/green color bar on top of the heatmap corresponds to the histological classification (Red: benign, Green: PTC).Back to article page