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Figure 2 | BMC Medical Genomics

Figure 2

From: Identification of SERPINA1 as single marker for papillary thyroid carcinoma through microarray meta analysis and quantification of its discriminatory power in independent validation

Figure 2

Heatmap and hierarchical clustering of meta analysis data on further candidate marker genes. As shown in the heatmap, there are a range of different genes with good discriminatory power between PTC and benign nodules. Therefore, removing SERPINA1 from the meta analysis dataset leads to a range of possible expression signatures with 99% classification accuracy in leave-one-out crossvalidation (see main text). In all cases, the same one sample is misclassified (see discussion for details). Columns correspond to samples and rows to genes, the red/green color bar on top of the heatmap corresponds to the histological classification (Red: benign, Green: PTC).

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