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Table 2 Differential Expression Analysis

From: Identification of SERPINA1 as single marker for papillary thyroid carcinoma through microarray meta analysis and quantification of its discriminatory power in independent validation

SYMBOL

RefSeq

logFC

adj.P.Val

Sens.

Spec.

KEGGID

SERPINA1

NM_000295, NM_001002235, NM_001002236

3.30

7.81e-39

0.98

1.00

04610

PROS1

NM_000313

2.12

8.89e-34

0.98

1.00

04610

LRP4

NM_002334

2.80

8.89e-34

1.00

0.96

NA

NPC2

NM_006432

1.29

5.83e-33

1.00

0.94

04142

LAMB3

NM_000228, NM_001017402

2.46

5.11e-31

0.96

1.00

04510, 04512, 05200, 05222

DPP4

NM_001935

2.86

6.96e-31

0.98

0.98

NA

SDC4

NM_002999

1.68

5.50e-30

0.96

0.96

04512, 04514

IPCEF1

NM_015553

-2.10

2.88e-29

1.00

0.00

NA

QPCT

NM_012413

2.09

3.00e-29

0.98

1.00

NA

MPPED2

NM_001584

-2.28

7.73e-29

1.00

0.00

NA

TIMP1

NM_003254

1.85

1.48e-27

0.96

0.94

NA

TFF3

NM_003226

-3.42

2.07e-27

1.00

0.00

NA

PRSS23

NM_007173

1.48

2.32e-27

0.98

0.98

NA

MET

NM_000245

1.64

2.37e-27

0.94

0.98

04060, 04144, 04360, 04510, 04520, 05120, 05200, 05210, 05211, 05218

CDH3

NM_001793

2.72

3.45e-27

0.96

0.94

04514

GGCT

NM_024051

1.21

2.74e-26

0.98

0.92

00480

PDLIM4

NM_003687

2.21

3.37e-26

0.96

0.98

NA

KRT19

NM_002276

2.33

3.40e-25

0.98

0.98

NA

CITED1

NM_004143

3.17

4.42e-25

0.94

0.96

NA

CHI3L1

NM_001276

3.50

4.42e-25

0.96

0.90

NA

  1. The first 20 entries in the toptable of differential expression in meta analysis data, including log2 fold changes (logFC) and Benjamini-Hochberg adjusted p-values (adj.P.Value) as calculated by the limma-software. Sensitivity and Specificity are given for the distinction of PTC vs NG at maximum accuracy. Annotational information like gene symbols, consensus sequence identifiers (RefSeq) and KEGG Pathway IDs are shown.