Figure 5

Cytoband gains and losses by vCGH and CGH on 190 DLBCLs. (A) vCGH Viterbi. (B) vCGH Posterior with a series of posterior probability cut-offs (p = 0.5, 0.6, 0.7, 0.8 and 0.9). (C) Comparison of vCGH and CGH where Viterbi method was used to represent vCGH. In (A) and (B), losses were shown on left-sided bars and gains were shown on right-sided bars. On Y axis are the cytobands ordered from pter to qter for each chromosome (from top to bottom). On X axis are the gain and loss frequencies, i.e. the number of samples harboring a gain or loss on a cytoband. In (C), gain and loss were shown separately in the top and bottom panels. In each panel, CGH results were shown in yellow (above X axis) and vCGH prediction were shown in red (below X axis). On X axis are the cytobands ordered from pter to qter, from chr1 to chr18. On Y axis, the height of each bar indicates gain or loss frequencies, i.e., the number of samples harboring a gain or loss on a cytoband.