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Figure 8 | BMC Medical Genomics

Figure 8

From: Virtual CGH: an integrative approach to predict genetic abnormalities from gene expression microarray data applied in lymphoma

Figure 8

Association of additional recurrent abnormalities with gene expression and survival time on 190 DLBCLs. (A) Permutation tests for the association of recurrent abnormalities with the gene expression. The recurrent gains of 1p, 2q and 6q and losses of 1q, 6p and 8q were shown. For each abnormality, the red square showed the test statistic for the real data. The histogram showed the distribution of the test statistic from 1000 permutations. X axis presents the value of test statistics, which is the sum log p-value between the samples that exhibit the recurrent abnormality and those that are wild type for that abnormality. (B) Kaplan-Meier estimates of overall survival of 190 DLBCLs grouped by the abnormalities. The log rank test was used for the p values among the patient groups characterized by the regions of 1q, 6q and 8q.

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